POM TR. 063 362 901 (Distribution Permit Number from Board of Drug and Food Control the Republic of Indonesia)
is a freeze dried purified extract of specific part of fresh shark cartilage containing proteoglycan, hexosamine and free D-glucuronic acid. The main indication of is to reduce pain and inflammation in osteoarthritis (OA). Bioactive substances of are chondroitin-4-sulfate, chondroitin-6-sulfate, and chondroitin-2,6-disulfate (this specific chondroitin sulfate is only found in shark cartilage) and proteoglycan as angiogenesis inhibitor.